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Rev. méd. Chile ; 141(11): 1427-1433, nov. 2013. tab
Article in Spanish | LILACS | ID: lil-704570

ABSTRACT

American Trypanosomiasis or Chagas Disease is a major public health problem, endemic in the American continent since prehistoric times. Its natural course is towardschronicity in the immunocompetent host, often leading to severe cardiopathy or bowelinvolvement. Pharmacologic therapy is restricted to two drugs and only one of themis currently available in Chile. Both have poor effectiveness in the chronic stages ofthe disease and cause frequent adverse reactions. Many physicians avoid their use,despite published evidences about the usefulness. We herein report the experienceof our Center in the treatment of Chronic Chagas Disease in adults using the drugnifurtimox, emphasizing its degree of acceptability and its secondary effects.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Chagas Disease/drug therapy , Nifurtimox/therapeutic use , Trypanocidal Agents/therapeutic use , Chagas Disease/epidemiology , Chile/epidemiology , Chronic Disease , Medication Adherence , Nifurtimox/adverse effects , Trypanocidal Agents/adverse effects
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